Adopting a ‘Whole Trust’ infection prevention approach to reduce MRSA bacteraemia rate

Improving surveillance of MRSA bacteraemia

Editor—Wyllie et al conclude that admission cultures accounted for 24% of total hospital methicillin resistant Staphylococcus aureus (MRSA) bacteraemia episodes over seven years to March 2004. Data collected from five district general hospitals and one university hospital in Cheshire and Merseyside and one district general hospital in greater Manchester support this view. This group of hospital...

When sepsis persists: a review of MRSA bacteraemia salvage therapy.

MRSA bacteraemia (MRSAB), including infective endocarditis, carries a high mortality rate, with up to 50% of patients failing initial therapy with vancomycin and requiring salvage therapy. Persistent MRSAB can be difficult to successfully eliminate, especially when source control is not possible due to an irremovable focus or the bacteraemia still persists despite surgical intervention. Althoug...

Is MRSA admission bacteraemia community-acquired? A case control study.

OBJECTIVES To compare characteristics of methicillin resistant Staphylococcus aureus (MRSA) and methicillin susceptible S. aureus (MSSA) bacteraemia detected on admission to a UK hospital and to determine whether these organisms are community-acquired. METHODS Consecutive cases of MRSA bacteraemia admitted to general medicine between 2003 and 2006 were identified and compared to MSSA age-matc...

Thirty-day all-cause fatality subsequent to MRSA, MSSA and E. coli bacteraemia and C. difficile infection: 2016 to 2017

Adopting Trust Negotiations: To Negotiate or Not To Negotiate?

Open distributed environments require that agents who are not known to each other must be able to interact. A new authorization scheme called trust negotiation has emerged allowing two strangers to iteratively and bilaterally establish trust. This scheme has been applied to different environments such as the Web, P2P networks or Grid environments. However, it is not yet clear what impact, impli...